Lightning Process for Clinicians – Evidence & Referral Guide
For GPs, physiotherapists, psychologists & specialist teams

A structured mind–body training you can refer to with confidence

The Lightning Process (LP) is a manualised neuroplasticity and mind–body training, delivered by accredited trainers, with an independently peer–reviewed evidence base built up since 2010. Here is what the research shows, who it suits, and how referral works.

18
Peer–reviewed published studies
0
Reported side effects across studies
90%+
Reported improvement, Long COVID audit
RCT
NHS · University of Bristol
Studied by NHS University of Bristol London Metropolitan University BMJ Explore Journal MS–UK Brighton & Sussex Medical School
What is the LP?

Not positive thinking – a trained, structured skill

The Lightning Process combines elements of neurolinguistics, mind–body coaching, and applied neuroplasticity into a manualised protocol. It is not repackaged CBT: a qualitative comparison study found LP has a distinct focus on language, a specific neurophysiological rationale, and its own mode of delivery.

Delivered over 3 days

Patients attend a structured group or 1:1 training run by an accredited LP trainer – in person or online.

Skills–based training

Patients learn a specific set of tools they then apply themselves, day to day. Post course practitioner support available but seldom needed.

Sits alongside existing care

LP is additive. Patients continue any medication, therapy, or specialist input they are already receiving.

Who to refer

Where the evidence base is strongest

Referral decisions remain a clinical judgement call. This is a guide to where published outcomes are strongest – and where more caution is warranted.

Evidence base is strongest for

  • CFS/ME (adult and paediatric)
  • Long COVID
  • Fibromyalgia and chronic pain
  • Cancer–related fatigue in survivors
  • MS–related fatigue
  • Functional symptoms with no ongoing tissue damage

Use clinical judgement

  • Patients not yet medically investigated or diagnosed
  • Acute illness, active infection, or unstable conditions
  • Severe or unstabilised mental illness
  • Patients who are not ready or willing to actively participate
  • As a replacement for – rather than alongside – existing treatment
The evidence

18 independently peer–reviewed studies

A selection of the published research. Filter by condition, or view the full library on the Lightning Process research page.

Randomised controlled trial
NHS · University of Bristol · published in BMJ (Archives of Disease in Childhood)
The SMILE trial: LP added to specialist medical care improved physical function and fatigue in paediatric CFS/ME, with benefits sustained at 12 months and no reported side effects.
FatiguePhysical function0 side effects
Systematic review
Explore Journal
The first systematic review of all LP evidence found strong support for benefit across fatigue, physical function, pain, anxiety and depression, with no reported harms.
FatiguePainAnxiety & depression
Audit study · 2025
Journal of Family Medicine & Primary Care
A 12–case primary care audit found over 90% of Long COVID patients reported improvement, with significant gains across all participants and no side effects.
Long COVID90%+ improved0 side effects
Case reports · 2023
Explore Journal (UK) & Open Journal of Clinical & Medical Case Reports (NZ)
Two peer–reviewed primary care case reports found reduced fatigue and improved physical and emotional symptoms, sustained at 3–month follow–up.
FatigueSustained at 3 months
Qualitative analysis
Fatigue: Biomedicine, Health & Behaviour
LP was found to be distinct from CBT – identified by its language style, neurophysiological rationale, and mode of delivery, not simply "CBT repackaged."
Distinct from CBT
Outcome measures study
Multi–country (UK, NZ, USA, Canada, Switzerland) · n=96
The Alpine Study, covering CFS/ME, fibromyalgia, pain, anxiety and depression, found decreased pain and fatigue and increased wellbeing at 1 month, maintained at 3 and 6 months.
Pain reducedSustained to 6 months
Pilot study
Cancers (MDPI) · adolescent & young adult cancer survivors
Statistically significant improvements across all outcome measures for chronic fatigue in cancer survivors, with reductions described as remarkable versus prior years of no change.
Fatigue reducedQuality of life
Randomised controlled trial
London Metropolitan University · National Wellbeing Service
LP significantly reduced alcohol use and impulsivity, and increased flourishing scores versus treatment as usual, with benefits sustained at 3 months.
Alcohol use reducedSustained 3 months
Proof of concept · 12 months
MS–UK
Measurable benefit across a 12–month study period for people with Multiple Sclerosis, with no negative incidents reported.
MS fatigue0 negative incidents
Charity survey · n=4,217
ME Association · 2010
LP received the highest rating for "greatly improved" among 25 approaches assessed – ahead of both CBT and graded exercise therapy.
#1 rated approach
Safety & rigour

Why clinicians can refer with confidence

Peer–reviewed

Published in journals including BMJ, Explore, and Fatigue: Biomedicine, Health & Behaviour.

No Harms

No adverse effects reported across all 18 published studies, including the NHS/Bristol RCT.

Additive

Designed to run alongside existing medical care – not as a replacement for it.

Clinician FAQs

The questions we're asked most

Isn't this just positive thinking or willpower?

No. LP is a manualised protocol combining specific neurolinguistic and mind–body techniques, delivered by accredited trainers. A published qualitative comparison found it has a distinct rationale and delivery style from CBT – it isn't "think yourself better."

What's the strongest evidence you can point me to?

The SMILE trial – an NHS/University of Bristol randomised controlled trial published in the BMJ's Archives of Disease in Childhood – compared LP plus specialist medical care against specialist medical care alone in paediatric CFS/ME, with improvements sustained at 12 months.

What if my patient doesn't improve?

As with any intervention, response varies. No adverse effects have been reported across the published research, and LP is intended to sit alongside – not replace – a patient's existing care plan, so nothing is lost by trying it.

Is it safe for patients I'm already treating?

Yes. Patients continue any medication, therapy or specialist input they're already receiving. LP does not require anyone to stop existing treatment.

How is it delivered, and how long does it take?

A structured 3–day training run by an accredited trainer, in person or online, after which the patient self–administers the tools they've learned.

Is there a cost to my patient, and to me?

There is no cost to you as a referring clinician. Course fees and any current offers are confirmed directly with our team – contact us using the details below.

Refer a patient

How referral works

Check suitability

Use the "who to refer" guidance above, or call our team to talk through a specific patient.

Share the guide

Download the clinician PDF above, or pass the patient our research page directly.

Patient's free consultation

Patients and an LP practitioner discuss suitability for LP. They book their own training place – no referral form or admin required from you.

Stay in the loop

We're happy to correspond with you directly about a shared patient, with their consent.

Questions about a specific patient?

Talk to our team – we're happy to help you decide whether the LP is the right fit before you refer.

Phil Parker Lightning Process · Full research library · lightningprocess.com

This page summarises independently peer–reviewed published research on the Lightning Process for clinician reference. It is not a substitute for individual clinical judgement, and does not constitute medical advice. Research summaries last reviewed February 2025 – see the full research library for citations and updates.